| Research Topics: |
| INDEX |
| AI-chat 1 |
| MCS 1 |
| PRIME 29 |
| aging 11 |
| arts 1 |
| brain 10 |
| brainwave 2 |
| cancer 6 |
| climate 1 |
| cognition 3 |
| covid-19 1 |
| crime 1 |
| culture 1 |
| dental 1 |
| diabetes 4 |
| disease 1 |
| economy 2 |
| exercise 1 |
| eyes 2 |
| gender 1 |
| genetics 2 |
| gut 2 |
| heart 4 |
| immune 6 |
| lungs 1 |
| metabolism 1 |
| microbiome 2 |
| nutrition 1 |
| obesity 1 |
| politics 8 |
| pollution 1 |
| practice 1 |
| privacy 1 |
| psychology 5 |
| reproduction 2 |
| sleep 1 |
| soc-media |
| unk |
| vaccine 1 |
| virus 2 |
| war-confl |
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Scanned: 2706 Evaluated: 166 Selected: 52 |
| PRIME DIABETES GUT MICROBIOME | ||||||||
Mdb06-004 | Multi-strain probiotic enhances metformin tolerance by modulating gut microbiome and bile acid pathways: Insight from multi-omics post-hoc analysis ProGasMet trial | |||||||
| Quote: | Conclusion Probiotic supplementation may be associated with coordinated microbiome-metabolome shifts in metformin-intolerant type 2 diabetes, highlighting bile acid remodelling, particularly hyodeoxycholic acid, as a plausible mechanistic candidate for improved tolerability. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345743v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345743v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Hanna Kwiendacz Danuta Cembrowska-Lech Karolina Skonieczna-ydecka Karolina Klimontowicz Konrad Podsiado Anna Wierzbicka-Wo Daniel Styburski Mariusz Kaczmarczyk Janusz Gumprecht Igor oniewski Katarzyna Nabrdalik, | |||||||
| PRIME CANCER GUT MICROBIOME | ||||||||
Mep06-006 | Gut microbiome and metabolome reveal hormone-related and functional alterations in ER-positive breast cancer: a casecontrol study | |||||||
| Quote: | Higher levels of DHEA-sulfate, estriol, and isoflavone phytoestrogen metabolites and lower lignan phytoestrogen metabolites were associated with breast cancer, while circulating estrogens and estrogen-related microbial functions were not. Beyond hormone-related pathways, higher levels of conjugated bile acids and carnitines were also associated with breast cancer. Compared to controls, cases exhibited depletion of Blautia obeum, Alistipes shahii, A. finegoldii, A. putredinis, and Anaerotruncus rubiinfantis, along with reduced abundance of functions related to menaquinol-8 biosynthesis, TCA cycle-related energy metabolism, and NAD salvage, indicating depletion of specific metabolic pathways rather than overall functional diversity. These results indicate a potential etiologic role for host-microbe metabolic interactions in breast cancer that extends beyond estrogen-centered mechanisms and warrants validation in independent cohorts. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345778v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.06.26345778v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Ashley H Larnder Kristin Campbell Thaddeus J Edens Julian J Lum David R Goodlett Jun Han Kathryn Isaac Rebecca Warburton Michelle Goecke Allen Hayashi Alison Ross Benot Chassaing Maeva Duquesnoy Jessica Morgan Jane Shearer Parveen Bhatti Amee R Manges Rachel A Murphy, | |||||||
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02/13/2026-07:20:23 PM
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