| Research Topics: |
| INDEX |
| AI-chat 2 |
| PRIME 13 |
| aging 5 |
| body 2 |
| brain 6 |
| cancer 5 |
| climate 5 |
| cognition 2 |
| covid-19 3 |
| culture 2 |
| dental 1 |
| diabetes 4 |
| economy 1 |
| exercise 2 |
| eyes 1 |
| gender 1 |
| genetics 4 |
| heart 3 |
| immune 7 |
| language 1 |
| lungs 1 |
| nutrition 9 |
| obesity 2 |
| physical 2 |
| politics 1 |
| pollution 2 |
| psychology 2 |
| sleep 1 |
| vaccine 3 |
| virus 2 |
|
Scanned: 2656 Evaluated: 168 Selected: 44 |
| AGING CANCER GENDER | ||||||||
Mge09-016 | Evidence for sexual antagonism and antagonistic pleiotropy in the maintenance of late onset Alzheimers disease alleles | |||||||
| Quote: | Multiple lines of evidence also suggest there is an inverse relationship between cancer and LOAD risk. The combined effect of sexual antagonism and antagonistic pleiotropy could explain the persistence of alleles that increase LOAD risk in post-reproductive females, if they also reduce cancer risk in males. This framework could be applied to other female-biased late-life conditions, and our results may be useful in informing polygenic risk scores or therapies where genotype-by-sex effects may result in undesired outcomes for one particular sex. | |||||||
| Abstract: | https://www.medrxiv.org/content/10.64898/2026.02.26.26347171v1 | |||||||
| Full Text: | https://www.medrxiv.org/content/10.64898/2026.02.26.26347171v1.full-text | |||||||
| Search Similar: | Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho | |||||||
| Search Authors: | Edward H Morrow Jon Alexander Harper, | |||||||
|
Javilk's Research Links for Week 09 Updated 03/07/2026-12:02:44 AM What interests you? What have you found? Tell me! Drop me a note to subscribe or submit something. |