Research
Topics:
INDEX
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diabetes 1
diagnostics 1
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heart 8
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virus 4
 
Scanned: 2578
Evaluated: 292
Selected: 56
 
    HEART    LUNGS   

Mbr10-022

Effects of CPAP on OSA-related cardiovascular risk markers: a two-week CPAP withdrawal and re-initiation study

Quote:Conclusion Short-term CPAP re-initiation improved endothelial function FMD, with no significant effects on autonomic measures BRS, #916;HR or structural vascular indices. This supports a temporal dissociation between rapidly reversible exposure metrics AHI, HB and slower dynamics of autonomic markers. Changes in spontaneous PWADi suggests that it may track physiological CPAP benefits beyond indices driven primarily by respiratory-event frequency.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.10.26348040v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.10.26348040v1.full-text
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Search Authors: Adrien Waeber Geoffroy Solhelac Gregory Heiniger Theo Imler Monica Betta Giulio Bernardi Andrea Faini Paolo Castiglioni Carolina Lombardi Gianfranco Parati Vincent Pichot Ali Azarbarzin Raphal Heinzer, 
    HEART    LUNGS   

Mbr10-026

Oxygen pulse kinetics and ventilatory inefficiency as markers of cardiovascular limitation on exercise in patients with mild pre-capillary pulmonary hypertension and exertional dyspnoea.

Quote:Conclusion O2 pulse kinetics, particularly a work-phase slope 0.40 and plateauing or decreasing trajectories, are associated with cardiac dysfunction in patients with pre-capillary PH. VEVCO/peakVO appears to be a marker of cardiovascular limitation and mortality and may aid differentiation between cardiac dysfunction and deconditioning in this population when conventional CPET parameters are inconclusive.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.10.26347216v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.10.26347216v1.full-text
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Search Authors: Thanos Charalampopoulos Sirpi Malar Selvaraju Ian Smith Ellis Cerrone Rahul Mohanraj Robin Condliffe Charlie Elliot Abdul Hameed Judith Hurdman Alexander Matthew Knox Rothman Andrew Swift David Kiely A.A.Roger THOMPSON, 
    HEART   

Mcr10-002

A Multicenter Study of the Electrical Characteristics and Short-Term Outcomes of the Aveir VR Leadless Pacemaker

Abstract: https://www.medrxiv.org/content/10.64898/2026.03.06.26347827v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.06.26347827v1.full-text
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Search Authors: Jiandu Yang Ruogu Li Xingbin Liu Xiaolin Xue Jiang-Hua Zhang Yong-mei Hu Baojian Zhang Lin Tong Hui Luo Min Shen Zhongli Chen Xiahenazi Aiyasiding Mengxing Cai Xiaojian Chi Yan Dai Baopeng Tang Keping Chen, 
    HEART    OBESITY   

Mcr10-004

Obesity-Related Metabolites are Associated with Incident Coronary Heart Disease and Respond to Metabolic and Bariatric Surgery

Abstract: https://www.medrxiv.org/content/10.64898/2026.03.06.26347826v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.06.26347826v1.full-text
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Search Authors: Zicheng Wang Yulu Zheng Lei Wang Charles Robb Flynn Xiao Ou Shu Qiuyin Cai Deepak Kumar Gupta Loren Lipworth Wei Zheng Xinmeng Zhang You Chen Jason M Samuels Danxia Yu, 
    HEART   

Mcr10-010

Cross-cohort insights into the association of handgrip strength transitions and burdens with cardiovascular disease risk

Quote:Conclusions HGS burdens outperformed in predicting cardiovascular health compared to single cross-sectional HGS itself, suggesting the clinical utility of longitudinal HGS monitoring in clinical and public health strategies for CVD prevention.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.05.26347756v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.05.26347756v1.full-text
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Search Authors: Hua Lin ping zeng, 
    DIABETES    HEART   

Mcr10-020

Utility of glucose, lipid and kidney function Trajectory Measures for incident Cardiovascular Disease risk prediction for people living with Type 2 Diabetes: a case-study using Danish registry data

Abstract: https://www.medrxiv.org/content/10.64898/2026.03.06.26347493v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.06.26347493v1.full-text
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Search Authors: Peter P Harms Omar Silverman-Retana Jonas Schaarup Marieke T. Blom Anders A. Isaksen Daniel R. Witte, 
    PRIME    AGING    HEART   

Mcr10-030

Effect of age, sex and BMI on resting ECG intervals and their variabilities in healthy adults

Quote:Conclusion Age, BMI, and sex all have major impacts on the ECG intervals and their variability. A resting heart behaves largely like a pulse width modulation system, with a stable active interval and an adjustable idle interval to meet the varying needs for cardiac output. The durations and variabilities of the active interval, more than those of the RR interval, are indicators of a hearts health condition. A young and healthy heart tends to have a shorter duration and smaller variability in the active interval.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.07.26347862v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.07.26347862v1.full-text
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Search Authors: Qihou Zhou, 
    HEART   

Mge10-004

Genetically proxied inhibition of angiotensinogen synthesis is associated with lower cardiovascular risk

Quote:Conclusions Genetic downregulation of angiotensinogen synthesis is associated with lower cardiovascular disease burden without concerning safety signals, supporting the potential of angiotensinogen inhibitors to reduce cardiovascular risk. Key Question Is there human genetic evidence suggesting that inhibition of hepatic angiotensinogen synthesis can reduce long-term cardiovascular risk? Key Finding Genetically proxied angiotensinogen synthesis inhibition is associated with lower risk of coronary artery disease, stroke and heart failure, as well as favorable effects on cardiac and cerebrovascular pathologies, without raising major safety concerns. Effect estimates were comparable in magnitude to those observed for genetic proxies of approved RAAS-blocking therapies. Take-home Message Human genetic evidence supports the hypothesis that angiotensinogen synthesis inhibition may reduce both cardiovascular event risk and chronic subclinical vascular disease burden, providing a strong rationale for prioritizing angiotensinogen inhibitors in cardio- and cerebrovascular outcome trials.
Abstract: https://www.medrxiv.org/content/10.64898/2026.03.08.26347887v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.03.08.26347887v1.full-text
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Search Authors: Panagiotis Zangas Murad Omarov Lanyue Zhang Marios K Georgakis, 

  Javilk's Research Links for Week 10
Updated 03/15/2026-01:54:15 AM
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