PRIME DIABETES GENDER METABOLISM
Aaa14-005	Cold Plunge vs Sauna Benefits: How Men and Women Respond Differently
	Quote:	Ice bathing has been associated with changes in metabolism and insulin sensitivity, but many studies are small and do not establish causality. Ice bathing may also influence immune function by regulating the activity of inflammatory molecules, such as interleukin-6 (IL-6) and tumor necrosis factor #945; (TNF-#945;). In a recent study, six weeks of regular cold-water immersions at 14C for 1 hour increased IL-6 levels and CD3 T-cell counts, the latter of which potentiate immune defense against pathogens. These immune changes may reflect acute stress responses rather than durable improvements in immune protection.... Heat therapy similarly improves endothelial function through the activity of nitric oxide (NO), a molecule that dilates vessels to reduce blood pressure, as well as promotes the formation of new blood vessels. Heat increases NO availability by stimulating NO synthase, an enzyme that produces NO in the endothelium.6,7 Chronic heat therapy has also been shown to increase endothelial nitric oxide synthase (eNOS) expression and enhance angiogenesis.
	Article:	https://www.news-medical.net/health/Cold-Plunge-vs-Sauna-Benefits-How-Men-and-Women-Respond-Differently.aspx
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Updated 04/11/2026-01:28:16 AM
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Aaa14-005

Cold Plunge vs Sauna Benefits: How Men and Women Respond Differently