PRIME AGING GUT SLEEP
Bge26-004	Gut-derived serine protease reduces sleep but extends lifespan
	Quote:	Rescue of sleep by antioxidant treatment demonstrates that peripheral ROS accumulation drives the behavioral phenotype. Strikingly, despite physiological dysfunction and reduced sleep, CG11037 or Cytochrome P450 knockdown extends lifespan in a ROS dependent manner, suggesting that stress adaptation of these knockdowns allows them to live longer. Together, these findings uncover a mechanism for the unexpected association of reduced sleep and extended lifespan.
	Article:	https://www.biorxiv.org/content/10.64898/2026.06.25.734557v1
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	Search Authors:	Rebecca Sydney Moore Richard Xiong Erick Astacio Julie A. Williams Thomas Brooks Gregory Grant Joseph Stucynski Houssein Fazelinia Erik Nash Lynn Spruce Amita Sehgal,
GUT MICROBIOME
Bgn25-019	A Scalable Framework for Species-Resolved Human Gut Microbiome Profiling Using Full-Length 16S rRNA Sequencing
	Article:	https://www.biorxiv.org/content/10.64898/2026.06.21.732309v1
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	Search Authors:	Parth Sarin Paras Sehgal Vasudev Paveri Sakshi Rai Ashriti Chettri Rahul C Bhoyar Rajesh Karkaryate Shahzad Mirza Sourav Sen Gupta Sridhar Sivasubbu Devraj J Parsannanavar,
GUT MICROBIOME
Mga26-005	A pharmacometric grey zone reconciles high metronidazole resistance rates with bismuth quadruple therapy efficacy in Helicobacter pylori
	Comment:	Ulcers
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.21.26356170v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.21.26356170v1.full-text
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	Search Authors:	Chunmeng He Huan Wang Xinbo Xu,
GUT MICROBIOME
Min26-007	Personalized prediction of UTI risk and antibiotic susceptibility based on gut E. coli
	Abstract:	https://www.medrxiv.org/content/10.1101/2024.04.05.24305377v2
	Full Text:	https://www.medrxiv.org/content/10.1101/2024.04.05.24305377v2.full-text
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	Search Authors:	Veronika Tchesnokova Debarati Choudhury Lydia Larson Irina Basova Yulia Sledneva Teresa Cristina Bonilla Thalia Solyanik Jennifer Heng Isaac Pasumansky Victoria Bowers Sophia Pham Julia Seregin Gregory S. Davis Lawrence T. Madziwa Erika Holden Sara Y. Tartof James D. Ralston Evgeni V. Sokurenko,
GUT MICROBIOME NUTRITION
Mnu26-005	Food additive exposure associated with reduction in gut microbiota diversity
	Quote:	Concordantly, microbial signatures associated with the sweeteners and sugar polyols additive combination showed depletion of fiber associated commensal taxa, and enrichment of pathways involved in polyol and aromatic compound metabolism. Notably, these associations emerged despite packaged foods representing only #8764;15 of logged dietary intake, underscoring the sensitivity of gut microbial diversity to limited exposure, and demonstrating that without integrating additive and processed-food metrics, one of the largest effect-size phenomena in human gut microbiota diversity would remain undetected.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.06.22.26356234v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.06.22.26356234v1.full-text
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	Search Authors:	Rohan Singh Daniel McDonald Rob Knight Marcel Salath,

Javilk's Research Links for Week 26
Updated 07/04/2026-03:43:26 AM
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Bge26-004

Gut-derived serine protease reduces sleep but extends lifespan

Bgn25-019

A Scalable Framework for Species-Resolved Human Gut Microbiome Profiling Using Full-Length 16S rRNA Sequencing

Mga26-005

A pharmacometric grey zone reconciles high metronidazole resistance rates with bismuth quadruple therapy efficacy in Helicobacter pylori

Min26-007

Personalized prediction of UTI risk and antibiotic susceptibility based on gut E. coli

Mnu26-005

Food additive exposure associated with reduction in gut microbiota diversity