CANCER
Bcb28-002	High glucose confers senescence resistance via GLUT1 epigenetic rewiring to blunt immunotherapy responses in esophageal squamous cell carcinoma
	Article:	https://www.biorxiv.org/content/10.64898/2026.07.15.738372v1
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	Search Authors:	Jin-Xiu Dong Jianian Zhou Jia-Jie Hao Shuai Kong Chuntong Yin Dan-Dan Wei Fei Wang Junboya Ma Jinman Fang Yuan-Wei Zhang Huaguang Pan Wen-Qiang Wei Mingrong Wang Kai Ma Yuan Jiang Yan-Yi Jiang,
CANCER
Bcb28-008	Epithelial Stem Cell Fate Determines Chemoradiotherapy Response in Rectal Cancer
	Article:	https://www.biorxiv.org/content/10.64898/2026.07.15.736775v1
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	Search Authors:	Nick Li Fiza Ishaqwala Thomas A. Wright Alistair Wilkinson Petra Vlckova Katherine Trevers Rhianna OSullivan Shauna Crampsie Ewa Basiarz Sierra Vanderkamp Ashley K McCulloch Aurelie Dobric Smita Krishnaswamy Bart Vanhaesebroeck span classnlm-collab data-hwp-idcollab-1Glasgow Serial Sampling Consortium Campbell S. D. Roxburgh Maria Hawkins Christopher J. Tape,
CANCER
Bcb28-009	5-Dihydrotestosterone reveals a mutant androgen receptor vulnerability in prostate cancer
	Article:	https://www.biorxiv.org/content/10.64898/2026.07.14.738538v1
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	Search Authors:	Samual Adams Lindsey Phelan Therese Lewis Josie Behm Aggie Law Xianglin Shi Guangyuan Frank Li Jianneng Li,
PRIME CANCER GUT MICROBIOME NUTRITION
Bcb28-010	Gut microbiome derived folate metabolite suppresses colorectal cancer progression
	Quote:	Mechanistically, folinic acid acts as a signaling molecule that directly binds and inhibits the intracellular protease calpain-2. This interaction stabilizes epithelial E-cadherin protein expression and suppresses CRC epithelial-to-mesenchymal transition driving metastasis. Genetically manipulating gut microbial production of FA is sufficient to modulate CRC in vivo, even in the presence of chronic inflammation.
	Article:	https://www.biorxiv.org/content/10.64898/2026.07.14.738490v1
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	Search Authors:	Rebecca Danner Juyeong Cho Zachary Detwiler Jonathan Williams Jiyoung Amanda Han Chang Yang Xavier Diebold Katerina Maeder Jonathan G. Van Vraken Allison S. Walker Cammie Lesser Snehal N. Chaudhari,
CANCER IMMUNE
Bim28-004	The CD19-4-1BBL antibody fusion protein unleashes the immune system against high-risk chronic lymphocytic leukemia
	Article:	https://www.biorxiv.org/content/10.64898/2026.07.09.737515v1
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	Search Authors:	Priyanka Khare Ronghua Zhang Cristina Ivan Sarah Schneider Priyanka Banerjee Navid Sobhani Harry L Polasek Vanessa Behrana Jensen Karen Clise-Dwyer William Wierda Maria Teresa Sabrina Bertilaccio,
CANCER KIDNEYS
Mur28-002	Bladder Cancer in the United States: National Trends and State-Level Patterns from Global Burden of Disease (GBD) Study, 1980-2021
	Quote:	Conclusion Bladder cancer continues to impose a substantial and uneven burden across the U.S. State-level variations, driven by environmental factors, aging populations, and healthcare access gaps, require targeted prevention and improved early detection. Future research should assess the cost-effectiveness of prioritizing prevention over late-stage treatment to optimize healthcare spending.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.07.11.26357810v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.07.11.26357810v1.full-text
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	Search Authors:	Alireza Sadeghi Fatemeh Nouri Niloofar Dehdari Ebrahimi Ehsan Taherifard Mohammadreza Soltani Stephen B. Williams Wassim Kassouf,
PRIME CANCER
Mur28-004	GPCR-Based Machine Olfaction On Urine Scent Surpasses PSA at Predicting Prostate Cancer
	Quote:	onclusions A genuine, confound-controlled olfactory PCa signature is recoverable from 80 samples, surpasses this cohorts serum PSA (0.645) and exceeds the population PSA range, and improves monotonically with training-set size. We present this as a small-sample feasibility benchmark, not yet a validated diagnostic; the dominant remaining factor is training-set size, and the path to clinical-utility and improved AUC is clearly found to be a larger, multi-site, age-matched, ideally prospective training cohort
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.07.10.26357731v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.07.10.26357731v1.full-text
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	Search Authors:	Andreas Mershin Claire Guest Nikolas Stefanou Rob Harris Adan Rotteveel Shannon Johnson Kai Chau Kung Zoi Kountouri Howard Kivell Elcin Zan Clifford Gluck Iqbal Anjum Francesca Teasdale Antoanela Colda Tom Leslie Shuguang Zhang Claire Dowse Keane Ong Paul Pu Liang Achilleas Kotsis,
PRIME CANCER POLLUTION
Sd281-004	Why Are Healthy Young Non-smokers Developing Lung Cancer?
	Quote:	According to Nieva, commercially grown (non-organic) fruits, vegetables, and whole grains generally contain higher levels of pesticide residues than dairy products, meat, and many processed foods. He also pointed to previous research showing that agricultural workers with long term pesticide exposure experience higher rates of lung cancer, adding support to the hypothesis. The study also found that women under 50 who have never smoked develop lung cancer more often than men in the same age group. Women in the study also tended to eat more fruits, vegetables, and whole grains than their male counterparts.
	Article:	https://www.sciencedaily.com//releases/2026/07/260712011758.htm
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CANCER
Sd285-010	This Sugar-coated Therapy Boosted Survival Against Deadly Brain Cancer by 50 in Mice
	Article:	https://www.sciencedaily.com//releases/2026/07/260715083542.htm
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AI-CHAT PRIME CANCER
Sd285-017	AI Flags More Than 250,000 Suspicious Cancer Research Papers
	Quote:	The researchers found that more than 250,000 papers contained writing patterns similar to those seen in studies that had already been retracted over suspected fabrication. "Paper mills are companies that sell fake or low-quality scientific studies. They are producing research on an industrial scale, and our findings suggest the problem in cancer research is far larger than most people realized," Professor Barnett said.
	Article:	https://www.sciencedaily.com//releases/2026/07/260714225538.htm
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Javilk's Research Links for Week 28
Updated 07/17/2026-11:18:40 PM
What interests you? What have you found? Tell me!
Drop me a note to subscribe or submit something.

Bcb28-002

High glucose confers senescence resistance via GLUT1 epigenetic rewiring to blunt immunotherapy responses in esophageal squamous cell carcinoma

Bcb28-008

Epithelial Stem Cell Fate Determines Chemoradiotherapy Response in Rectal Cancer

Bcb28-009

5-Dihydrotestosterone reveals a mutant androgen receptor vulnerability in prostate cancer

Bcb28-010

Gut microbiome derived folate metabolite suppresses colorectal cancer progression

Bim28-004

The CD19-4-1BBL antibody fusion protein unleashes the immune system against high-risk chronic lymphocytic leukemia

Mur28-002

Bladder Cancer in the United States: National Trends and State-Level Patterns from Global Burden of Disease (GBD) Study, 1980-2021

Mur28-004

GPCR-Based Machine Olfaction On Urine Scent Surpasses PSA at Predicting Prostate Cancer

Sd281-004

Why Are Healthy Young Non-smokers Developing Lung Cancer?

Sd285-010

This Sugar-coated Therapy Boosted Survival Against Deadly Brain Cancer by 50 in Mice

Sd285-017

AI Flags More Than 250,000 Suspicious Cancer Research Papers