PRIME BRAIN IMMUNE
Bbc30-006	Mass Spectrometry-Based Multiomic Profiling Defines Proteome, Lipidome, and Metabolome Remodeling in IFN- and LPS-Stimulated BV-2 Microglial Cells
	Quote:	Process-level integration of significant features revealed coordinated remodeling of inflammatory protein programs with lipid storage, membrane remodeling, nucleotide metabolism, amino acid availability, phospholipid precursor abundance, nitric oxide-associated metabolism, and redox/osmolyte pathways. These findings demonstrate that IFN-#947; and LPS-induced activation of BV-2 cells involves integrated immune, lipid, and metabolic adaptation rather than isolated induction of canonical inflammatory mediators. This integrated multiomic framework provides a resource for investigating how lipid and metabolic remodeling regulate microglial inflammatory states.
	Article:	https://www.biorxiv.org/content/10.64898/2026.07.27.741024v1
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	Search Authors:	Abraham M Borst Matthew R Eskritt Kaitlyn T Mang Melissa R Pergande,
CANCER IMMUNE
Bcb30-010	Beyond Immune Evasion: CD47-Driven Pro-Tumorigenic Dysfunction in Diffuse Large B Cell Lymphoma and Triple-Negative Breast Cancer
	Article:	https://www.biorxiv.org/content/10.64898/2026.07.25.740652v2
	Search Similar:	Brave Mojeek Startpage Dogpile Bing Googl Lycos Utub Yaho
	Search Authors:	Travis Cheng In Lum Jordan Yong Ming Tan Felix Jun Heng Ng Sai Mun Leong Muhammad Sufyan Bin Masroni Susan Swee Shan Hue,
PRIME IMMUNE METABOLISM SLEEP
Bph30-002	Nocturnin drives mitochondrial NADP(H)/NAD(H) rhythms to regulate steroid rhythm amplitude and time metabolism
	Quote:	Circadian rhythms are conserved biological timekeeping mechanisms crucial for the temporal compartmentalization of metabolic processes. However, the molecular pathways by which circadian rhythms are regulated within metabolism are not fully understood.... Collectively, we found that NOCTs control of mitochondrial NADP(H)/NAD(H) rhythms is a novel regulator of steroid amplitude and downstream metabolic rhythms.
	Article:	https://www.biorxiv.org/content/10.64898/2026.07.24.740574v1
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	Search Authors:	Lauren Palluth Isara Laothamatas Tammy-Nhu Nguyen Emil S Rasmussen Lauren G Zacharias Mauricio J Velasquez Melissa Inigo-Vollmer Xiaorong Fu Thomas P Mathews Jeffrey G McDonald Shawn C Burgess Joseph S Takahashi Carla B Green,
IMMUNE POLLUTION
Mep29-007	Spatiotemporal Interactions of Air Pollution, Airborne Pollen, and Land Cover on Asthma and Allergies Medication Sales: A Population-Level Ecological Study
	Quote:	Introduction The interaction between air pollution and airborne pollen is emerging as a major public health concern, as it may enhance allergic responses and exacerbate asthma at the population level. Available evidence suggests that urban residents experience a higher burden of respiratory allergies than rural populations, potentially due to the combined effects of chemical air pollutants and pollen exposure.
	Abstract:	https://www.medrxiv.org/content/10.64898/2026.07.20.26358483v1
	Full Text:	https://www.medrxiv.org/content/10.64898/2026.07.20.26358483v1.full-text
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	Search Authors:	Isabella Annesi-Maesano Julie Prudhomme,
CANCER IMMUNE
Sd301-005	CRISPR Makes Prostate Cancer Vulnerable to Immunotherapy/a
	Quote:	Scientists used CRISPR to make prostate cancer cells easier for the immune system to detect and destroy. The experimental treatment dramatically improved the effects of immunotherapy in mice
	Article:	https://www.sciencedaily.com//releases/2026/07/260726015250.htm
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PRIME AGING BRAIN IMMUNE
Sd301-007	A Hidden Alzheimers Tipping Point May Decide Who Gets Dementia/a
	Quote:	In other words, a cellular state that was associated with neurodegeneration in some people appeared to be separated from damaging effects in others. This suggests that resilience is not simply a matter of avoiding Alzheimers pathology. It may also depend on how the brain controls, redirects, or adapts its response to that pathology.
	Article:	https://www.sciencedaily.com//releases/2026/07/260726015257.htm
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PRIME IMMUNE
Sd302-038	A Single Sauna Session Sends Immune Cells Surging/a
	Quote:	"This may indicate that sauna bathing mobilizes additional white blood cells into the bloodstream from tissues, where they are then redeposited after the session. This kind of periodic release of white blood cells into the bloodstream is beneficial, as once they leave their storage sites, they are better able to patrol the body and respond to pathogens," says Ilkka Heinonen, an Academy Research Fellow at the University of Turku.
	Article:	https://www.sciencedaily.com//releases/2026/07/260727012141.htm
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	See Also:	https://www.uef.fi/en/article/sauna-bathing-may-boost-immune-responses
PRIME GUT IMMUNE NUTRITION
Sd305-037	Rice Bran Compound May Help Ease Irritable Bowel Symptoms/a
	Quote:	A compound in rice bran may help calm an overactive gut by reducing the calcium signals that cause intestinal muscles to contract. Ferulic acid suppressed contractions triggered by several chemical messengers in laboratory experiments. The discovery could eventually support new dietary approaches for diarrhea-related digestive disorder
	Article:	https://www.sciencedaily.com//releases/2026/07/260729010742.htm
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Javilk's Research Links Newsletter for Week 30
Updated 08/01/2026-01:13:17 AM
What interests you? What have you found? Tell me!
Drop me a note to subscribe or submit something.

Bbc30-006

Mass Spectrometry-Based Multiomic Profiling Defines Proteome, Lipidome, and Metabolome Remodeling in IFN- and LPS-Stimulated BV-2 Microglial Cells

Bcb30-010

Beyond Immune Evasion: CD47-Driven Pro-Tumorigenic Dysfunction in Diffuse Large B Cell Lymphoma and Triple-Negative Breast Cancer

Bph30-002

Nocturnin drives mitochondrial NADP(H)/NAD(H) rhythms to regulate steroid rhythm amplitude and time metabolism

Mep29-007

Spatiotemporal Interactions of Air Pollution, Airborne Pollen, and Land Cover on Asthma and Allergies Medication Sales: A Population-Level Ecological Study

Sd301-005

CRISPR Makes Prostate Cancer Vulnerable to Immunotherapy/a

Sd301-007

A Hidden Alzheimers Tipping Point May Decide Who Gets Dementia/a

Sd302-038

A Single Sauna Session Sends Immune Cells Surging/a

Sd305-037

Rice Bran Compound May Help Ease Irritable Bowel Symptoms/a