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    GENETICS    POPULATION   

Bge42-004

Understanding genetic and environmental complexity in phenotypic resemblance across relatedness in population-scale data

Quote: The shape of the relationship varies widely across traits, with profiles exhibiting features found under each of the theoretical mechanisms we explored. Overall, we conclude disentangling these multiple overlaid processes will be necessary to fully understand how phenotypic similarity increases with genetic relatedness in large cohorts.
Article: https://www.biorxiv.org/content/10.64898/2026.10.18.759872v1
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Search Authors: Mariadaria K Ianni-Ravn Andy Dahl John Novembre, 
    GENETICS    POPULATION   

Bgn42-007

A test for linkage disequilibrium in structured populations

Quote: Quantifying patterns of dependence between distinct loci, known as linkage disequilibrium (LD), is vital for identifying locus-trait associations and studying evolution.
Article: https://www.biorxiv.org/content/10.64898/2026.10.18.759967v1
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Search Authors: Alvin J. Zhang John D. Storey, 
    GENETICS   

Bgn42-014

Systematic Functional Interrogation of Neurodevelopmental Disorder Risk Variants

Article: https://www.biorxiv.org/content/10.64898/2026.10.21.760732v1
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Search Authors: Alejandro Gomez Jessica C. McAfee Hyunggyu Min Tatiana Ulloa Avila Sean Jones Jessica L. Bell Yangzhenyu Gao Ellen Hu Haoyue Li Sool Lee Ratchell Sadovnik Zheng Fan Nan Yang Adriana S. Beltran Hyejung Won, 
    GENETICS   

Bgn42-015

Genome-wide LD scores enable robust heritability and genetic correlation estimation from summary statistics across genetic ancestries

Article: https://www.biorxiv.org/content/10.64898/2026.10.20.760508v1
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Search Authors: Moonseong Jeong Zhengtong Liu Jiayi Ni Ulzee An Sungjoo Han Aakarsh Anand Prateek Anand Mayuko Boffelli Sriram Sankararaman, 
    AGING    GENETICS   

Mep42-015

Biological age measured by DNA methylation clocks and mortality: A systematic review and meta-analysis

Quote: Clocks incorporating additional surrogates and technical refinements showed numerically larger pooled associations than their original counterparts. GrimAge2 (HR per SD: 1.65 95 CI 1.53, 1.77 vs 1.46 1.38, 1.55) and PCGrimAge (1.56 1.36, 1.78 vs 1.51 1.32, 1.74) showed higher pooled HR association with all-cause mortality than GrimAge. Further work is warranted to evaluate the responsiveness of DNAm clocks to interventions and potential clinical utility.
Abstract: https://www.medrxiv.org/content/10.64898/2026.10.20.26365864v1
Full Text: https://www.medrxiv.org/content/10.64898/2026.10.20.26365864v1.full-text
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Search Authors: Jian Hua Tay Duarte Barros Jiajun Dong Shubham Choudhury Austeja Bakulaite Weilan Wang Andrea B. Maier, 

  Javilk's Research Links Newsletter for Week 42
Updated 10/24/2026-02:39:34 AM
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