Research
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Scanned: 2960
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    LUNGS   

Mbr44-003

Sex-stratified and interaction multi-omics analysis of DNA methylation and gene expression in asthma

Quote: Findings Asthma-associated DMCs were predominantly hypomethylated in females and hypermethylated in males. Among trans-eQTMs, 379 associations were shared across all four models, whereas the majority were model-specific, indicating extensive sex-dependent regulatory architecture.
Article: https://www.medrxiv.org/content/10.64898/2026.10.19.26365928v1
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Search Authors: Eskezeia Y. Dessie Yadu Gautam Bradley H. Rosen Angelico Mendy Mingon Kang Tesfaye B. Mersha, 
    LUNGS   

Mbr44-004

Tracheal Eccentricity is Associated with Respiratory Morbidity and Mortality in Chronic Obstructive Pulmonary Disease

Article: https://www.medrxiv.org/content/10.64898/2026.10.14.26361560v1
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Search Authors: Stphanie M. Aguilera Venkata L. Sthanam Muhammad F.A. Chaudhary Arie Nakhmani Joseph M. Reinhardt Surya P. Bhatt Sandeep Bodduluri, 
    IMMUNE    LUNGS   

Mim44-011

Divergent Eosinophilic and Paradoxical Inflammatory Adverse-Event Signatures Across Five Type 2 Asthma Biologics: A FAERS Active-Comparator Disproportionality Analysis

Quote: Conclusion FAERS active-comparator analysis reveals drug-specific, not class-uniform, adverse-event reporting patterns: anti-IL-5-axis agents disproportionately report EGPA/vasculitis, and dupilumab disproportionately reports ocular inflammation with markedly earlier onset. These hypothesis-generating signals cannot establish causality and require confirmation through case-level or comparative pharmacoepidemiological studies.
Article: https://www.medrxiv.org/content/10.64898/2026.09.21.26363575v1
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Search Authors: Adalia Cristiana Iancu Marwan Kobtan Nada Soliman Shahinazhanem Abdellatif, 

  Javilk's Research Links Newsletter for Week 45
Updated 11/14/2026-03:15:39 AM
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