Research
Topics:
INDEX
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aging 9
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war-confl
 
Scanned: 2960
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    LAW    NUTRITION    RIGHTS   

Aee45-1024

California Law Requires ID to Buy Muscle-Building Supplements in January

Quote: Any supplement marketed or represented as a way to lose weight or build muscle is covered. A legal analysis of the statute lists what a court can weigh in a close case. Creatine is named, along with green tea extract, raspberry ketone, garcinia cambogia, and green coffee bean extract. Label promises about appetite, metabolism, or strength also count. So does the shelf a store puts the product on.
Article: https://www.breitbart.com/health/2026/11/09/california-supplement-id-law-minors-creatine/
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    PRIME    BRAIN    DIABETES    HEART    NUTRITION   

Aef45-1001

Walnuts: Natures Brain-Boosting Super Food

Quote: "Walnut consumption has been associated with many health benefits, including reduced cardiovascular disease (CVD), coronary heart disease, and type II diabetes, as well as beneficial effects on aging and cancer risk. Scientistsrecently reviewed the association of walnuts with mortality and life expectancy and concluded that higher walnut consumption was associated with lower risks of total and CVD mortality and with greater life expectancy among an elderly U.S. population.
Article: https://richardgoldberg.substack.com/p/walnuts-natures-brain-boosting-super
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    PRIME    CANCER    GUT    MICROBIOME    NUTRITION   

Mga44-010

Replacing animal-sourced with plant-sourced proteins alters gut microbiota and biomarkers associated with colorectal cancer risk in healthy adults: A randomized feeding study

Quote: The 70 plant-protein diet also reduced fecal secondary and taurine-conjugated BAs, including the CRC-associated BAs DCA and LCA. Plasma glucuronidated BAs increased, expanding the circulating pool of readily excreted BA conjugates. Higher insoluble fiber intake was associated with greater microbiota restructuring and lower fecal NOCs. Methanogen carriers had higher baseline fecal NOCs and features of slower colonic transit, and showed weaker microbiota and less favorable BA responses to the 70 plant-protein diet. Baseline methanogen carriage thus could be exploited for participant stratification in future dietary interventions. ClinicalTrials.gov: NCT03206827.
Article: https://www.medrxiv.org/content/10.64898/2026.10.13.26365402v1
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Search Authors: Ching Jian Tiina Pellinen Antti Karkman Mikko Neuvonen Mikko Niemi Anne Salonen Anne-Maria Pajari, 
    MCS    PRIME    PRIO    GENETICS    METABOLISM    NUTRITION   

Mge45-005

A multi-center retrospective chart analysis identifying clinical, biochemical, and radiographic signatures of short-chain enoyl-CoA hydratase (ECHS1) deficiency

Quote: Short-chain enoyl-CoA hydratase (ECHS1) catalyzes the hydration of C4-C6 acyl-CoA molecules to produce ATP in fatty acid #946;-oxidation. Deficiency of the ECHS1 enzyme, ECHS1D, is a rare autosomal recessive disorder that presents with a large and pleomorphic clinical spectrum. We present the largest comprehensive study of known diagnosed ECHS1D patients to date...

Of note , the reported ability of some patients with ECHS1D to tolerate ketogenic diet highlights that it is likely the impaired amino acid catabolism and not the impaired fatty acid oxidation defect that contributes to disease, although the data remain limited. These findings highlight that ECHS1D represents a spectrum disease, with limited genotype-phenotype correlation, contribu ting to variability in outcomes. Nonetheless, families and providers often seek prognostic information in the face of a challenging and rare diagnosis. Therefore, cat egorization by age of onset does seem to be a meaningful way to provide insight on predicted morbidity and mortality.

Comment: Althought these cases are genetic in origin, there is some similarity to MCS and other Yuppy Flu type illnesses where Acetyl-Co A generation is impaired. Dr, Cathcart treated these successfully with massive vitamin C doses.
Article: https://www.medrxiv.org/content/10.64898/2026.11.05.26366953v1
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Search Authors: Christine Kong Cesar Alves Georg-Friedrich Vogel Rui Xiao Irina Anselm Gerard Berry Juan Francisco Cabello Vernica Cornejo Andrea Cortes Fernandez Gregory M. Enns Michael Gomez Chad Haldeman-Englert Suzanne Hollander A. Micheil Innes Emma Jannotta Aaina Kochhar Jessica Kopesky Austin Larson Chung Lee Mara Lezcano Rachel Li Matthew Lines Jennifer Morrison Michael Muriello Elizabeth Null Luis Pea-Quintana Erin Phelps Mohamad Saifeddine Marta Cristina Sanabria Russell P. Saneto Emily Shelkowitz Christina G. Tise Johan L.K. Van Hove Ibrahim Elsharkawi Rebecca Ganetzky, 
    PRIME    AGING    METABOLISM    NUTRITION    PHYSICAL   

Mgr44-010

Plasma metabolomic profiling of frailty in older adults at risk of dementia

Quote: Conclusions Frailty index was associated with carboxylic acids and derivatives, fatty acyls and organooxygen compounds across multiple clusters, and a large number of lipids were linked to frailty score, potentially implicating dysregulation of energy metabolism in the pathophysiology of frailty and forming a panel of predictive biomarkers of at risk patients.
Article: https://www.medrxiv.org/content/10.64898/2026.10.06.26364906v1
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Search Authors: Isabelle Alldritt Johannes C. Michaelian Rachael Yu Sarah E. Deemer Richard J. Mills Sharon L. Naismith Andrew Philp, 
    KIDNEYS    NUTRITION   

Mkd44-008

Trace element supplementation preserves metabolic resilience in chronic kidney disease

Quote: Conclusions Trace element supplementation preserved metabolic resilience in CKD, limiting metabolic displacement without complete restoration. Preservation of metabolic organization may represent a complementary dimension of therapeutic response in CKD.
Article: https://www.medrxiv.org/content/10.64898/2026.10.19.26365915v1
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Search Authors: Jianyu Piao Mingji Jin Fengxian Yin Zhenyu Quan Zhonggao Gao Zhenhua Cui, 
    NUTRITION   

Mnu44-002

The Dose-Response Investigation of Docosahexaenoic acid (DRI-DHA) Trial: A randomized controlled trial demonstrates DHA feedback inhibition of its own synthesis

Quote: Isotope source partitioning showed plasma DHA was equally supplement-derived and #945;-linolenic acid (ALA)-derived at 132 mg/d, implying net DHA-equivalent supply of 264 mg/d and maximal ALA-derived contribution of 251 mg/d without dietary DHA. Endogenous synthesis may contribute more to DHA homeostasis than previously assumed, approaching recommendations. This study provides a mechanistic framework for future studies defining DHA requirements.
Article: https://www.medrxiv.org/content/10.64898/2026.10.23.26366234v1
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Search Authors: Amy Symington Chuck T. Chen Yan Fu Mathieu J. Clavet Tommy S. Fong Daiqing Wu Dehan Kong David J. Jenkins John L. Sievenpiper Adam H. Metherel Richard P. Bazinet, 
    NUTRITION    REPRODUCTION   

Mnu44-004

Dietary Enhancement for Iron Deficiency and Anaemia Treatment (DEFeAT): study protocol for a randomised controlled trial to assess the effect of a mineral-enriched powder on iron deficiency in women of reproductive age

Quote: Discussion Fortification, an effective approach for the prevention of ID/IDA, has advantages over some methods of supplementation because it uses low levels of iron, minimising unpleasant side effects, does not risk toxicity, and has high acceptability and compliance rates. This mineral-enriched powder uses electrolytic iron and zinc sulphate monohydrate of a small particle size, which is less irritating to the gut, and facilitates bioavailability.
Article: https://www.medrxiv.org/content/10.64898/2026.10.20.26365734v1
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Search Authors: Jessie L Burns Hailey Scott Lawrence Mbuagbaw Clara H Miller Hauna Sheyholislami Brianne A Clouthier Bndicte Fontaine-Bisson Kristin L Connor, 
    PRIME    GENDER    NUTRITION   

Mnu44-005

Sex-Specific Associations of Added Sugars and Fructose Exposure Across the First 1,000 Days With Body Composition at 24 Months

Quote: Conclusions Associations of early-life sugars exposure with body composition varied by developmental timing and child sex. Findings from the smaller DXA subset are exploratory and require replication but suggest that susceptibility to early dietary sugars may differ across developmental windows....

Exploratory DXA findings showed more positive associations of prenatal added sugars with adiposity in girls and of infancy added sugars with adiposity in boys. The findings do not support sex-specific dietary recommendations; they reinforce the importance of limiting added sugars in early life and of replicating sex- and timing-specific patterns in larger cohorts.

Article: https://www.medrxiv.org/content/10.64898/2026.10.16.26365755v1
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Search Authors: Sara A. Fortin-Miller Byron J. Gajewski Susan E. Carlson John Colombo Danielle N. Christifano Debra K. Sullivan Holly R. Hull, 
    DIABETES    NUTRITION    OBESITY   

Mnu44-009

Real-World Twelve-Month Weight Loss Outcomes in a Comprehensive Obesity Care Program Utilizing Individualized Nutrition Therapy and Incretin-Based Obesity Medications

Quote: Conclusions Integrating individualized carbohydrate-reduced nutritional therapy with IOM-based care was associated with greater 12-month weight loss than IOM-based care without structured nutritional therapy. These real-world findings support further evaluation of individualized nutritional approaches as an adjunct to incretin-based obesity pharmacotherapy.
Article: https://www.medrxiv.org/content/10.64898/2026.10.09.26365158v1
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Search Authors: Shaminie J Athinarayanan Alison R. Zoller Kristin E. Bergenthon Amy M Goss Barbara A. Gower, 
    NUTRITION   

Mph44-005

Part 2 of a 2-part open-label clinical trial evaluating repeated nicotinamide riboside parenteral administration: 90 days of at-home subcutaneous injections

Article: https://www.medrxiv.org/content/10.64898/2026.10.13.26365470v1
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Search Authors: Anne Russ Yasmeen Nkrumah-Elie Frehiwet Hailu Jun Kwon Tracy Allen Andrew Shao Halland Chen, 
Search Words:
nicotinamide riboside Mojeek Startp Brave Bing Googl Lycos Utub Yahoo 
    AGING    NUTRITION   

Mph44-007

Part 1 of a 2-part, open-label clinical trial evaluating repeated nicotinamide riboside parenteral administration: 3 consecutive days of intramuscular and subcutaneous injections

Article: https://www.medrxiv.org/content/10.64898/2026.10.12.26365345v1
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Search Authors: Yasmeen Nkrumah-Elie Jun Kwon Anne Russ Sierra Simpson Frehiwet Hailu Tracy Allen Halland Chen Andrew Shao, 
    PRIME    CANCER    DRUGS    IMMUNE    NUTRITION   

Ps446-013

What Fenbendazole and Ivermectin Have in Common with a Cure

Quote: And the fact that these low-cost, off-patent drugs are dismissed so aggressively raises an important question: Is this about science, or about profit? That question runs through everything in this article. Because whether we are talking about a 5 dog dewormer, a daily walk in the sunshine, or a natural hormone your body makes, the pattern is the same: If it cant be patented, it gets buried.
Comment: Several effective anti-cancer treatments listed.
Article: https://principia-scientific.com/what-fenbendazole-and-ivermectin-have-in-common-with-a-cure/
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    IMMUNE    NUTRITION   

Sd451-007

Common Supplement Could Help Fight Psoriasis, Scientists Discover

Quote: Scientists have discovered that pantethine, a readily available vitamin B5 derivative, can calm overactive immune cells and may help fight psoriasis. The supplement prevented psoriasis in mice and showed promising results in a small human trial, revealing an unexpected connection between cholesterol and autoimmune inflammation.
Article: https://www.sciencedaily.com//releases/2026/11/261108233057.htm
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    PRIME    AGING    DIABETES    METABOLISM    NUTRITION   

Sd451-038

A Little-Known Protein Could Be a Major Culprit in Type 2 Diabetes

Quote: The protein, known as Miro1, was found at higher levels in the skeletal muscles of people with Type 2 diabetes. In preclinical experiments, scientists discovered that removing Miro1 restored the muscles response to insulin. They also found that exercise lowered Miro1 levels in people with the disease, offering new insight into how physical activity improves insulin sensitivity.
Article: https://www.sciencedaily.com//releases/2026/11/261106174543.htm
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  Javilk's Research Links Newsletter for Week 45
Updated 11/14/2026-03:15:39 AM
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